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CAB39 Antibody

Mouse Monoclonal Antibody (Mab)

     
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  • 1 - CAB39 Antibody AM1874b
    All lanes : Anti-CAB39 at 1:1000 dilution Lane 1: K562 whole cell lysate Lane 2: Mouse brain whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9Y376
Other Accession Q29RI6, NP_001124321.1, NP_001124322.1
Reactivity Human, Mouse
Predicted Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG1,K
Clone Names 198CT13.9.1
Calculated MW 39869 Da
Additional info
Gene ID 51719
Other Names Calcium-binding protein 39, MO25alpha, Protein Mo25, CAB39, MO25
Target/Specificity This CAB39 monoclonal antibody is generated from mouse immunized with CAB39 recombinant protein.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCAB39 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAB39
Synonyms MO25
Function Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
Cellular Location Cytoplasm.
Research Areas

BACKGROUND

Together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of STK11.

REFERENCES

Zeqiraj, E., et al. Science 326(5960):1707-1711(2009)
Zeqiraj, E., et al. PLoS Biol. 7 (6), E1000126 (2009) :
ten Klooster, J.P., et al. Dev. Cell 16(4):551-562(2009)
Fogarty, S., et al. J. Biol. Chem. 284(1):77-84(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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