注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   神经科学   >   SOX9 Antibody (Ascites)   

SOX9 Antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - SOX9 Antibody (Ascites) AM1964a
    SOX9 Antibody (Cat. #AM1964a) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the SOX9 antibody detected the SOX9 protein (arrow).
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P48436
Other Accession O18896, Q04887, NP_000337.1
Reactivity Human
Predicted Mouse, Pig
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 334CT39.1.4
Calculated MW 56137 Da
Additional info
Gene ID 6662
Other Names Transcription factor SOX-9, SOX9
Target/Specificity This SOX9 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from human SOX9.
Dilution WB~~1:1000~16000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOX9 Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX9 (HGNC:11204)
Function Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}
Research Areas

BACKGROUND

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

REFERENCES

Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)
Staffler, A., et al. Hum. Mutat. 31 (6), E1436-E1444 (2010) :
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Huang, W., et al. Mol. Cell. Biol. 20(11):4149-4158(2000)

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价