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>   首页   >   产品   >   一抗   >   信号转导   >   TNFSF4 Antibody (Ascites)   

TNFSF4 Antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - TNFSF4 Antibody (Ascites) AM1983a
    TNFSF4 antibody (Cat. #AM1983a) western blot analysis in HL-60 cell line lysates (35μg/lane).This demonstrates the TNFSF4 antibody detected the TNFSF4 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P23510
Other Accession NP_003317.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 362CT19.3.3
Calculated MW 21050 Da
Additional info
Gene ID 7292
Other Names Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1
Target/Specificity This TNFSF4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from human TNFSF4.
Dilution WB~~1:500~4000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNFSF4 Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFSF4
Synonyms TXGP1
Function Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas

BACKGROUND

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.

REFERENCES

Karulf, M., et al. J. Immunol. 185(8):4856-4862(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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