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GAST Antibody(Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - GAST Antibody(Ascites) AM2046a
    GAST Antibody (Cat. #AM2046a) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the GAST antibody detected the GAST protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P01350
Other Accession NP_000796.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 486CT4.8.13.6
Calculated MW 11394 Da
Additional info
Gene ID 2520
Other Names Gastrin, Gastrin-71, Gastrin component I, Gastrin-52, G52, Big gastrin, Gastrin component II, Gastrin-34, G34, Gastrin, Gastrin component III, Gastrin-17, G17, Gastrin-14, G14, Gastrin-6, G6, GAST, GAS
Target/Specificity This GAST antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human GAST.
Dilution WB~~1:100~1600
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGAST Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAST
Synonyms GAS
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
Cellular Location Secreted.
Research Areas

BACKGROUND

Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq].

REFERENCES

Kovac, S., et al. FEBS Lett. 584(21):4413-4418(2010)
Ferrand, A., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G220-G227 (2010) :
El Ali, Z., et al. J. Endocrinol. Invest. 33(3):186-191(2010)
Huang, C.L., et al. Pharmacology 85(3):131-135(2010)
Leja, M., et al. Dig. Dis. Sci. 54(11):2377-2384(2009)

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