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>   首页   >   产品   >   一抗   >   癌症   >   IL2 Antibody (Center) (Ascites)   

IL2 Antibody (Center) (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - IL2 Antibody (Center) (Ascites) AM2117a
    IL2 Antibody (Center)(Ascites)(Cat. #AM2117a) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the IL2 antibody detected the IL2 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P60568
Other Accession NP_000577.2
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 627CT14.8.1
Calculated MW 17628 Da
Additional info
Gene ID 3558
Other Names Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin, IL2
Target/Specificity This IL2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the Central region of human IL2.
Dilution WB~~1:100~1600
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL2 Antibody (Center) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL2
Function Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.
Cellular Location Secreted.
Research Areas

BACKGROUND

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

REFERENCES

Zhu, P., et al. J. Immunol. 185(9):5140-5149(2010)
Muller, T., et al. Scand. J. Immunol. 72(4):365-371(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Horowitz, A., et al. J. Immunol. 185(5):2808-2818(2010)
Wu, Z., et al. J Mol Cell Biol 2(4):217-222(2010)

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