注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   癌症   >   CD138 Antibody (C-term) (Ascites)   

CD138 Antibody (C-term) (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - CD138 Antibody (C-term) (Ascites) AM2142a
    CD138 Antibody (C-term)(Ascites)(Cat. #AM2142a) western blot analysis in HepG2 cell line lysates (35μg/lane).This demonstrates the CD138 antibody detected the CD138 protein (arrow).
  • 4 - CD138 Antibody (C-term) (Ascites) AM2142a
    CD138 Antibody (C-term) (Ascites) (Cat. #AM2142a) flow cytometric analysis of U266 cells (right histogram) compared to a negative control cell (left histogram).Alexa Fluor® 488-conjugated donkey anti-mouse lgG secondary antibodies were used for the analysis
  • 4 - CD138 Antibody (C-term) (Ascites) AM2142a
    CD138 Antibody (C-term) (Ascites) (Cat. #AM2142a) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).Alexa Fluor® 488-conjugated donkey anti-mouse lgG secondary antibodies were used for the analysis
  • 4 - CD138 Antibody (C-term) (Ascites) AM2142a
    CD138 Antibody (C-term) (Ascites) (Cat. #AM2142a) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).Alexa Fluor® 488-conjugated donkey anti-mouse lgG secondary antibodies were used for the analysis
  • 3 - CD138 Antibody (C-term) (Ascites) AM2142a
    Confocal immunofluorescent analysis of CD138 Antibody (C-term) (Ascites)(Cat#AM2142a) with U266 cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green).DAPI was used to stain the cell nuclear (blue).
  • 3 - CD138 Antibody (C-term) (Ascites) AM2142a
    Confocal immunofluorescent analysis of CD138 Antibody (C-term) (Ascites)(Cat#AM2142a) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green).DAPI was used to stain the cell nuclear (blue).
  • 3 - CD138 Antibody (C-term) (Ascites) AM2142a
    Confocal immunofluorescent analysis of CD138 Antibody (C-term) (Ascites)(Cat#AM2142a) with T47D cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green).DAPI was used to stain the cell nuclear (blue).
  • 产品详情
  • 文献引用 : 1
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, IF, E
Primary Accession P18827
Other Accession NP_001006947.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 587CT7.3.6.5
Calculated MW 32462 Da
Additional info
Gene ID 6382
Other Names Syndecan-1, SYND1, CD138, SDC1, SDC
Target/Specificity This CD138 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.
Dilution WB~~1:500~8000
FC~~1:10~50
IF~~1:10~50
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD138 Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDC1
Synonyms SDC
Function Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Cellular Location Membrane; Single-pass type I membrane protein. Secreted. Secreted, exosome. Note=Shedding of the ectodomain produces a soluble form.
Research Areas
Anti-human CD138 monoclonal antibodies and their bispecific formats: generation and characterization.
Author : Chen D1,2,Zou J1,2,3,Zong Y1,2,4,Meng H1,2,An G1,2,Yang L1,2,5.
Immunopharmacol Immunotoxicol. 2016 Jun;38(3):175-83. doi: 10.3109/08923973.2016.1153110. Epub 2016 Mar 8.
26954291

BACKGROUND

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

REFERENCES

Tsai, E.W., et al. Transplantation 90(8):875-881(2010) Hozumi, K., et al. FEBS Lett. 584(15):3381-3385(2010) Zyada, M.M., et al. Ann Diagn Pathol 14(3):153-161(2010) Al-Shibli, K., et al. APMIS 118(5):371-382(2010) Szumilo, J., et al. Folia Histochem. Cytobiol. 47(4):571-578(2009)

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价