癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
RNASE3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P12724 |
| Other Accession | NP_002926.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 18385 Da |
| Antigen Region | 124-151 aa |
| Gene ID | 6037 |
|---|---|
| Other Names | Eosinophil cationic protein, ECP, 3127-, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3 |
| Target/Specificity | This RNASE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-151 amino acids of human RNASE3. |
| Dilution | WB~~1:1000 IF~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RNASE3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RNASE3 |
|---|---|
| Synonyms | ECP, RNS3 |
| Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
| Cellular Location | Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.
REFERENCES
Peona, V., et al. J Asthma 47(2):131-134(2010)
Kang, I., et al. Eur Arch Otorhinolaryngol 267(3):391-395(2010)
Jonsson, U.B., et al. BMC Pulm Med 10, 36 (2010) :
Kato, M., et al. Int. Arch. Allergy Immunol. 152 SUPPL 1, 62-66 (2010) :
Chang, K.C., et al. BMC Cell Biol. 11, 6 (2010) :
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