|Application ||WB, IHC-P, E|
|Other Accession||P0CW01, P0CW00, P0CV99, P0CV98, A6NKD2, NP_001071165.2, XP_002344239.1|
|Calculated MW||35012 Da|
|Other Names||Testis-specific Y-encoded protein 1, Cancer/testis antigen 78, CT78, TSPY1, TSPY|
|Target/Specificity||This TSPY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the C-terminal region of human TSPY.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TSPY Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in sperm differentiation and proliferation.|
|Cellular Location||Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus|
|Tissue Location||Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.|
Provided below are standard protocols that you may find useful for product applications.
TSPY may be involved in sperm differentiation and proliferation.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)