注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   细胞生物学   >   EPB41L2 Antibody   

EPB41L2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - EPB41L2 Antibody AP50701
    Western blot analysis of lysate from HepG2 cell line,using EPB41L2 Antibody(AP50701). AP50701 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • 产品详情
  • 实验流程
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O43491
Reactivity Human
Host Rabbit
Clonality polyclonal
Calculated MW 113,76,84,96 KDa
Additional info
Other Names Band 41-like protein 2, Generally expressed protein 41, 41G, EPB41L2
Dilution WB~~1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name EPB41L2
Function Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell membrane
Tissue Location Widely expressed. EMBL; AF027299; AAC16923.1; -; mRNA EMBL; AY047584; AAK95850.1; -; mRNA EMBL; AK295124; BAG58150.1; -; mRNA EMBL; CR749262; CAH18118.1; -; mRNA EMBL; AL109938; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL357496; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL355360; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL358943; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL590014; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471051; EAW48062.1; -; Genomic_DNA CCDS; CCDS47474.1; -. [O43491-2] CCDS; CCDS5141.1; -. [O43491-1] CCDS; CCDS56450.1; -. [O43491-4] CCDS; CCDS59037.1; -. [O43491-3] RefSeq; NP_001129026.1; NM_001135554.1. [O43491-2] RefSeq; NP_001129027.1; NM_001135555.3. [O43491-2] RefSeq; NP_001239589.1; NM_001252660.1. [O43491-3] RefSeq; NP_001422.1; NM_001431.3. [O43491-1] RefSeq; XP_011533832.1; XM_011535530.1 RefSeq; XP_011533836.1; XM_011535534.1 RefSeq; XP_016865844.1; XM_017010355.1 RefSeq; XP_016865848.1; XM_017010359.1 RefSeq; XP_016865849.1; XM_017010360.1 RefSeq; XP_016865850.1; XM_017010361.1 RefSeq; XP_016865851.1; XM_017010362.1 UniGene; Hs.486470; - UniGene; Hs.708219; - ProteinModelPortal; O43491; - SMR; O43491; - BioGrid; 108351; 57 DIP; DIP-17034N; - IntAct; O43491; 32 STRING; 9606.ENSP00000338481; - iPTMnet; O43491; - PhosphoSitePlus; O43491; - BioMuta; EPB41L2; - EPD; O43491; - jPOST; O43491; - MaxQB; O43491; - PaxDb; O43491; - PeptideAtlas; O43491; - PRIDE; O43491; - ProteomicsDB; 48974; - ProteomicsDB; 48975; -. [O43491-2] TopDownProteomics; O43491-3; -. [O43491-3] Ensembl; ENST00000337057; ENSP00000338481; ENSG00000079819. [O43491-1] Ensembl; ENST00000368128; ENSP00000357110; ENSG00000079819. [O43491-1] Ensembl; ENST00000392427; ENSP00000376222; ENSG00000079819. [O43491-2] Ensembl; ENST00000445890; ENSP00000402041; ENSG00000079819. [O43491-3] Ensembl; ENST00000525271; ENSP00000432803; ENSG00000079819. [O43491-2] Ensembl; ENST00000528282; ENSP00000434308; ENSG00000079819. [O43491-3] Ensembl; ENST00000530481; ENSP00000434576; ENSG00000079819. [O43491-4] GeneID; 2037; - KEGG; hsa:2037; - UCSC; uc003qcg.2; human. [O43491-1] CTD; 2037; - DisGeNET; 2037; - EuPathDB; HostDB:ENSG00000079819.16; - GeneCards; EPB41L2; - HGNC; HGNC:3379; EPB41L2 HPA; HPA005730; - HPA; HPA006642; - MIM; 603237; gene neXtProt; NX_O43491; - OpenTargets; ENSG00000079819; - PharmGKB; PA27812; - eggNOG; KOG3527; Eukaryota eggNOG; ENOG410Y7NQ; LUCA GeneTree; ENSGT00940000155617; - HOGENOM; HOG000228841; - HOVERGEN; HBG007777; - InParanoid; O43491; - KO; K06107; - OMA; ISEFQFA; - OrthoDB; 262540at2759; - PhylomeDB; O43491; - TreeFam; TF351626; - Reactome; R-HSA-6794361; Neurexins and neuroligins ChiTaRS; EPB41L2; human GeneWiki; EPB41L2; - GenomeRNAi; 2037; - PRO; PR:O43491; - Proteomes; UP000005640; Chromosome 6 Bgee; ENSG00000079819; Expressed in 236 organ(s), highest expression level in corpus callosum ExpressionAtlas; O43491; baseline and differential Genevisible; O43491; HS GO; GO:0099738; C:cell cortex region; IDA:UniProtKB GO; GO:0030054; C:cell junction; IDA:HPA GO; GO:0005829; C:cytosol; TAS:Reactome GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB GO; GO:0005925; C:focal adhesion; HDA:UniProtKB GO; GO:0005654; C:nucleoplasm; IDA:HPA GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0005886; C:plasma membrane; IDA:HPA GO; GO:0008091; C:spectrin; TAS:ProtInc GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW GO; GO:0042731; F:PH domain binding; IEA:Ensembl GO; GO:0030507; F:spectrin binding; IEA:Ensembl GO; GO:0005198; F:structural molecule activity; IEA:InterPro GO; GO:0031032; P:actomyosin structure organization; IBA:GO_Central GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW GO; GO:0051301; P:cell division; IEA:UniProtKB-KW GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro GO; GO:1904778; P:positive regulation of protein localization to cell cortex; IMP:UniProtKB CDD; cd14473; FERM_B-lobe; 1 Gene3D; 1.20.80.10; -; 1 Gene3D; 2.30.29.30; -; 1 InterPro; IPR008379; Band_4.1_C InterPro; IPR019749; Band_41_domain InterPro; IPR030546; E41L2 InterPro; IPR000798; Ez/rad/moesin-like InterPro; IPR014847; FERM-adjacent InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf InterPro; IPR035963; FERM_2 InterPro; IPR019748; FERM_central InterPro; IPR019747; FERM_CS InterPro; IPR000299; FERM_domain InterPro; IPR018979; FERM_N InterPro; IPR018980; FERM_PH-like_C InterPro; IPR011993; PH-like_dom_sf InterPro; IPR007477; SAB_dom InterPro; IPR029071; Ubiquitin-like_domsf PANTHER; PTHR23280:SF17; PTHR23280:SF17; 1 Pfam; PF05902; 4_1_CTD; 1 Pfam; PF08736; FA; 1 Pfam; PF09380; FERM_C; 1 Pfam; PF00373; FERM_M; 1 Pfam; PF09379; FERM_N; 1 Pfam; PF04382; SAB; 1 PRINTS; PR00935; BAND41 PRINTS; PR00661; ERMFAMILY SMART; SM00295; B41; 1 SMART; SM01195; FA; 1 SMART; SM01196; FERM_C; 1 SUPFAM; SSF47031; SSF47031; 1 SUPFAM; SSF54236; SSF54236; 1 PROSITE; PS00660; FERM_1; 1 PROSITE; PS00661; FERM_2; 1 PROSITE; PS50057; FERM_3; 1 1: Evidence at protein level; Acetylation; Actin-binding; Alternative splicing; Cell cycle; Cell division; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Isopeptide bond; Membrane; Mitosis; Phosphoprotein; Polymorphism; Reference proteome; Transport; Ubl conjugation INIT_MET 1 1 Removed. {ECO:0000244|PubMed:19413330, ECO:0000244|PubMed:22223895, ECO:0000269|Ref.7} CHAIN 2 1005 Band 4.1-like protein 2 /FTId=PRO_0000219397 DOMAIN 218 499 FERM. {ECO:0000255|PROSITE- ProRule:PRU00084} REGION 502 610 Hydrophilic REGION 611 676 Spectrin--actin-binding REGION 855 1005 C-terminal (CTD) MOD_RES 2 2 N-acetylthreonine {ECO:0000244|PubMed:19413330, ECO:0000244|PubMed:22223895, ECO:0000269|Ref.7} MOD_RES 7 7 Phosphoserine MOD_RES 39 39 Phosphoserine MOD_RES 58 58 Phosphoserine MOD_RES 87 87 Phosphoserine MOD_RES 89 89 Phosphothreonine MOD_RES 170 170 Phosphoserine MOD_RES 208 208 Phosphoserine {ECO:0000250|UniProtKB:O70318} MOD_RES 386 386 Phosphoserine MOD_RES 402 402 Phosphoserine {ECO:0000250|UniProtKB:O70318} MOD_RES 499 499 Phosphoserine MOD_RES 550 550 Phosphoserine MOD_RES 562 562 Phosphoserine MOD_RES 575 575 Phosphoserine {ECO:0000250|UniProtKB:O70318} MOD_RES 598 598 Phosphoserine MOD_RES 614 614 Phosphoserine MOD_RES 623 623 Phosphotyrosine {ECO:0000250|UniProtKB:O70318} MOD_RES 627 627 Phosphoserine {ECO:0000250|UniProtKB:O70318} MOD_RES 647 647 Phosphoserine MOD_RES 715 715 Phosphoserine MOD_RES 718 718 Phosphoserine MOD_RES 763 763 Phosphothreonine {ECO:0000250|UniProtKB:O70318} MOD_RES 828 828 Phosphoserine CROSSLNK 140 140 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 144 144 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) VAR_SEQ 612 943 Missing (in isoform 2) /FTId=VSP_042910 VAR_SEQ 612 869 Missing (in isoform 3) /FTId=VSP_045090 VAR_SEQ 612 681 Missing (in isoform 4). /FTId=VSP_047181 VAR_SEQ 787 869 Missing (in isoform 4). /FTId=VSP_047182 VARIANT 17 17 Q -> H (in dbSNP:rs2297852) /FTId=VAR_020145 SEQUENCE 1005 AA; 112588 MW; E86CB17488F6045F CRC64; MTTEVGSVSE VKKDSSQLGT DATKEKPKEV AENQQNQSSD PEEEKGSQPP PAAESQSSLR RQKREKETSE SRGISRFIPP WLKKQKSYTL VVAKDGGDKK EPTQAVVEEQ VLDKEEPLPE EQRQAKGDAE EMAQKKQEIK VEVKEEKPSV SKEEKPSVSK VEMQPTELVS KEREEKVKET QEDKLEGGAA KRETKEVQTN ELKAEKASQK VTKKTKTVQC KVTLLDGTEY SCDLEKHAKG QVLFDKVCEH LNLLEKDYFG LLFQESPEQK NWLDPAKEIK RQLRNLPWLF TFNVKFYPPD PSQLTEDITR YFLCLQLRQD IASGRLPCSF VTHALLGSYT LQAELGDYDP EEHGSIDLSE FQFAPTQTKE LEEKVAELHK THRGLSPAQA DSQFLENAKR LSMYGVDLHH AKDSEGVDIK LGVCANGLLI YKDRLRINRF AWPKILKISY KRSNFYIKVR PAELEQFEST IGFKLPNHRA AKRLWKVCVE HHTFYRLVSP EQPPKAKFLT LGSKFRYSGR TQAQTRQAST LIDRPAPHFE RTSSKRVSRS LDGAPIGVMD QSLMKDFPGA AGEISAYGPG LVSIAVVQDG DGRREVRSPT KAPHLQLIEG KKNSLRVEGD NIYVRHSNLM LEELDKAQED ILKHQASISE LKRNFMESTP EPRPNEWEKR RITPLSLQTQ GSSHETLNIV EEKKRAEVGK DERVITEEMN GKEISPGSGP GEIRKVEPVT QKDSTSLSSE SSSSSSESEE EDVGEYRPHH RVTEGTIREE QEYEEEVEEE PRPAAKVVER EEAVPEASPV TQAGASVITV ETVIQENVGA QKIPGEKSVH EGALKQDMGE EAEEEPQKVN GEVSHVDIDV LPQIICCSEP PVVKTEMVTI SDASQRTEIS TKEVPIVQTE TKTITYESPQ IDGGAGGDSG TLLTAQTITS ESVSTTTTTH ITKTVKGGIS ETRIEKRIVI TGDGDIDHDQ ALAQAIREAR EQHPDMSVTR VVVHKETELA EEGED
Research Areas

REFERENCES

Parra M.,et al.Genomics 49:298-306(1998).
Liu J.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mungall A.J.,et al.Nature 425:805-811(2003).

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价