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ABCD3 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ABCD3 Antibody AP50722
    Western blot analysis of lysate from SH-SY5Y cell line,using ABCD3 Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P28288
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 75,63,27 KDa
Additional info
Gene ID 5825
Other Names ATP-binding cassette sub-family D member 3, 70 kDa peroxisomal membrane protein, PMP70, ABCD3, PMP70, PXMP1
Dilution WB~~ 1:1000
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ABCD3
Synonyms PMP70, PXMP1
Function Probable transporter involved in the transport of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial step in bile acid biosynthesis (PubMed:25168382). The nucleotide-binding fold acts as an ATP- binding subunit with ATPase activity (PubMed:11248239).
Cellular Location Peroxisome membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10704444}
Research Areas

BACKGROUND

Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.

REFERENCES

Gaertner J.,et al.Nat. Genet. 1:16-23(1992).
Kamijo K.,et al.Biochim. Biophys. Acta 1129:323-327(1992).
Gaertner J.,et al.Genomics 48:203-208(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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