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>   首页   >   产品   >   一抗   >   发育生物学   >   CABYR Antibody   

CABYR Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CABYR Antibody AP50723
    Western blot analysis of lysate from human testis tissue lysate,using CABYR Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O75952
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 53,51,41,24,30,31 KDa
Additional info
Gene ID 26256
Other Names Calcium-binding tyrosine phosphorylation-regulated protein, Calcium-binding protein 86, Cancer/testis antigen 88, CT88, Fibrousheathin II, Fibrousheathin-2, FSP-2, Testis-specific calcium-binding protein CBP86, CABYR, CBP86, FSP2
Dilution WB~~ 1:1000
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CABYR
Synonyms CBP86, FSP2
Function May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
Cellular Location Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella Isoform 3: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic
Tissue Location Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.
Research Areas

BACKGROUND

May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.

REFERENCES

Naaby-Hansen S.,et al.Dev. Biol. 242:236-254(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hsu H.-C.,et al.Biochem. Biophys. Res. Commun. 329:1108-1117(2005).

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