|Application ||WB, ICC, FC|
|Calculated MW||120 KDa|
|Other Names||ACL;Acly;ACLY_HUMAN;ATP citrate (pro-S) lyase;ATP citrate lyase;ATP citrate synthase; ATP-citrate (pro-S-)-lyase;ATP-citrate synthase;ATPcitrate synthase;ATPCL;Citrate cleavage enzyme;CLATP;EC 188.8.131.52;OTTHUMP00000164773.|
|Format||Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.|
Provided below are standard protocols that you may find useful for product applications.
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Elshourbagy N.A.,et al.Eur. J. Biochem. 204:491-499(1992).
Lord K.A.,et al.Protein Expr. Purif. 9:133-141(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Potapova I.A.,et al.Biochemistry 39:1169-1179(2000).