|Calculated MW||33 KDa|
|Other Names||Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8, FREAC-8, FOXE3, FKHL12, FREAC8|
|Format||Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149).|
Provided below are standard protocols that you may find useful for product applications.
Carlsson P.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Semina E.V.,et al.Hum. Mol. Genet. 10:231-236(2001).
Gregory S.G.,et al.Nature 441:315-321(2006).
Larsson C.,et al.Genomics 30:464-469(1995).
Valleix S.,et al.Am. J. Hum. Genet. 79:358-364(2006).