|Calculated MW||73 KDa|
|Other Names||Guanylate-binding protein 4, GTP-binding protein 4, GBP-4, Guanine nucleotide-binding protein 4, GBP4|
|Format||Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Golgi apparatus membrane. Note=Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus|
Provided below are standard protocols that you may find useful for product applications.
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).
Avdalovic A.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Jikuya H.,et al.DNA Res. 10:49-57(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Tripal P.,et al.J. Interferon Cytokine Res. 27:44-52(2007).