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NGFB Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - NGFB Antibody AP53311
    All lanes : Anti-NGFB Antibody at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P01138
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 27 KDa
Additional info
Gene ID 4803
Other Names Beta-nerve growth factor, Beta-NGF, NGF, NGFB
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name NGF
Synonyms NGFB
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Cellular Location Secreted.
Research Areas

BACKGROUND

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.

REFERENCES

Ullrich A.,et al.Nature 303:821-825(1983).
Ullrich A.,et al.Cold Spring Harb. Symp. Quant. Biol. 48:435-442(1983).
Borsani G.,et al.Nucleic Acids Res. 18:4020-4020(1990).
Tong Y.,et al.Zhongguo Ying Yong Sheng Li Xue Za Zhi 13:316-318(1997).
Kitano T.,et al.Mol. Biol. Evol. 21:936-944(2004).

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