- 文献引用 : 3
|Reactivity||Human, Mouse, Rat|
|Immunogen||Purified recombinant human beta actin protein fragments expressed in E.coli.|
|Calculated MW||45 KDa|
|Other Names||A X actin like protein;ACTB;ACTB_HUMAN;Actin;Actin cytoplasmic 1;Actx;b actin;b-actin;Beta cytoskeletal actin;Beta-actin;cytoplasmic 1;Melanoma X actin;N-terminally processed;PS1TP5 binding protein 1;PS1TP5BP1.|
|Format||Purified mouse monoclonal antibody in PB(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:29581253). Actin exists in both monomeric (G- actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947).|
|Cellular Location||Cytoplasm, cytoskeleton Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs|
Author : Wu W1,Fan H2,Jiang Y3,Liao L3,Li L1,Zhao J1,Zhang H1,Shrestha C1,Xie Z1.
Exp Dermatol. 2018 Aug 1. doi: 10.1111/exd.13760. [Epub ahead of print]
Author : Liu F1,Li W2,Hua S3,Han Y4,Xu Z4,Wan D4,Wang Y5,Chen W1,Kuang Y4,Shi J6,Zhi Q7.
Mol Cancer Ther. 2018 Feb 26. pii: molcanther.0906.2017. doi: 10.1158/1535-7163.MCT-17-0906. [Epub ahead of print]
Author : Yao X1,Cui X1,Wu X1,Xu P1,Zhu W1,Chen X2,Zhao T3.
Biochem Biophys Res Commun. 2017 Oct 16. pii: S0006-291X(17)32048-X. doi: 10.1016/j.bbrc.2017.10.070. [Epub ahead of print]
Provided below are standard protocols that you may find useful for product applications.
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.