Anti-FADD Antibody
Mouse Monoclonal Antibody
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Application ![]()
| WB, IP |
---|---|
Primary Accession | Q13158 |
Other Accession | NM_003824 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Immunogen | Recombinant human FADD protein. |
Purification | Affinity purified |
Calculated MW | 28 KDa |
Gene ID | 8772 |
---|---|
Other Names | FADD;FADD protein;FADD_HUMAN;Fas (TNFRSF6) associated via death domain;Fas associated via death domain;Fas associating death domain containing protein;Fas associating death domain containing protein;Fas associating protein;Fas associating protein with death domain;Fas associating protein with death domain;Fas TNFRSF6 associated via death domain;FAS-associated death domain protein;FAS-associating death domain-containing protein;FasTNFRSF6 associated via death domain;FasTNFRSF6 associated via death domain; GIG 3;GIG3;Growth inhibiting gene 3 protein;Growth-inhibiting gene 3 protein;H sapiens mRNA for mediator of receptor induced toxicity;H sapiens mRNA for mediator of receptor induced toxicity;Mediator of receptor induced toxicity;Mediator of receptor induced toxicity;MGC8528;MGC8528;MORT 1;MORT1;MORT1;Protein FADD. |
Dilution | WB~~1:500 |
Format | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | FADD |
---|---|
Synonyms | MORT1 |
Function | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
Tissue Location | Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.Active caspase-8 initiate

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