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STYK1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - STYK1 Antibody (N-term) AP7729a
    All lanes : Anti-STYK1 Antibody (N-term) at 1:1000 dilution Lane 1: K562 whole cell lysate Lane 2: SW480 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - STYK1 Antibody (N-term) AP7729a
    The anti- STYK1 Pab (Cat. #AP7729a) is used in Western blot to detect STYK1 in 293 , CEM (center), and mouse kidney cell line/tissue lysates.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q6J9G0
Other Accession Q52LR3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47577 Da
Additional info
Gene ID 55359
Other Names Tyrosine-protein kinase STYK1, Novel oncogene with kinase domain, Protein PK-unique, Serine/threonine/tyrosine kinase 1, STYK1, NOK
Target/Specificity This STYK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human STYK1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTYK1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STYK1
Synonyms NOK
Function Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways (By similarity).
Cellular Location Membrane; Single-pass membrane protein
Tissue Location Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in other tumor cells such as epidermoid carcinoma (A-431). Undetectable in most normal lung tissues, widely expressed in lung cancers
Research Areas

BACKGROUND

STYK1, a probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. It is widely expressed; highly expressed in brain, placenta and prostate. STYK1 is expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma.

REFERENCES

Ye, X., et al., Mol. Biol. Rep. 30(2):91-96 (2003).

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