|Application ||IHC-P, FC, WB, E|
|Other Accession||P11915, O62742, P32020, P07857|
|Reactivity||Human, Mouse, Rat|
|Predicted||Bovine, Mouse, Rabbit, Rat|
|Calculated MW||58994 Da|
|Other Names||Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2|
|Target/Specificity||This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-385 amino acids from the Central region of human SCP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SCP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.|
|Cellular Location||Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues Isoform SCP2: Mitochondrion.|
|Tissue Location||Liver, fibroblasts, and placenta.|
Provided below are standard protocols that you may find useful for product applications.
SCP2 mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. It may play a role in regulating steroidogenesis.
Wu, Y.B. et al. J Biol Chem. 2009 January 2; 284(1): 640?48.
Baker,M.E., et.al., DNA Cell Biol. 10 (9), 695-698 (1991)
Vila,A., et.al., Biochemistry 43 (39), 12592-12605 (2004)