|Application ||IHC-P-Leica, WB, E|
|Other Accession||A6NKC4, P12314|
|Other Names||High affinity immunoglobulin gamma Fc receptor IB, IgG Fc receptor IB, Fc-gamma RIB, FcRIB, hFcgammaRIB, FCGR1B, IGFRB|
|Target/Specificity||This FCGR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human FCGR1B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FCGR1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
Provided below are standard protocols that you may find useful for product applications.
FCGR1B may bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. This protein may function in the humoral immune response.
Thomas,G., et.al., Nat. Genet. 41 (5), 579-584 (2009)
Kuwano,Y., et.al., Arch. Dermatol. Res. 298 (10), 493-498 (2007)