SSPN Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB |
---|---|
Primary Accession | Q14714 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26618 Da |
Isotype | Rabbit IgG |
Antigen Source | Human |
Gene ID | 8082 |
---|---|
Antigen Region | 6-34 aa |
Other Names | SSPN;KRAG; Sarcospan; Sarcospan; K-ras oncogene-associated protein; Sarcospan; Kirsten-ras-associated protein |
Dilution | WB~~1:1000 |
Target/Specificity | This SSPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human SSPN. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SSPN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SSPN |
---|---|
Synonyms | KRAG |
Function | Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma Postsynaptic cell membrane; Multi-pass membrane protein. Note=Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. |
Tissue Location | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.
REFERENCES
Crosbie R.H., et al. J. Biol. Chem. 272:31221-31224(1997).
Crosbie R.H., et al. Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Wiemann S., et al. Genome Res. 11:422-435(2001).
Heighway J., et al. Genomics 35:207-214(1996).

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