|Application ||FC, IHC-P, WB|
|Other Accession||P17425, Q8JZK9, P13704, P23228|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||H=57,M=58,Rat=57 KDa|
|Other Names||HMGCS1; HMGCS; Hydroxymethylglutaryl-CoA synthase, cytoplasmic; 3-hydroxy-3-methylglutaryl coenzyme A synthase|
|Target/Specificity||This HMGCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the Central region of human HMGCS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HMGCS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.|
Provided below are standard protocols that you may find useful for product applications.
HMGCS1 condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Vock,C., Cell. Physiol. Biochem. 22 (5-6), 515-524 (2008)