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TGM2 antibody ( Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - TGM2 antibody ( Ascites) AM1889a
    Anti-TGM2 antibody ( Ascites) at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 77 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P21980
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 207CT39.5.5
Calculated MW 77329 Da
Additional info
Gene ID 7052
Other Names Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, Transglutaminase C, TG(C), TGC, TGase C, Transglutaminase H, TGase H, Transglutaminase-2, TGase-2, TGM2
Target/Specificity This TGM2 monoclonal antibody is generated from mouse immunized with TGM2 recombinant protein.
Dilution WB~~1:1000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTGM2 antibody ( Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TGM2
Function Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Research Areas

BACKGROUND

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

REFERENCES

Munezane, T., et al. J. Vasc. Surg. 52(4):967-974(2010)
Kim, D.S., et al. Biochem. Biophys. Res. Commun. 399(2):300-306(2010)
Stamnaes, J., et al. J. Biol. Chem. 285(33):25402-25409(2010)
Santhanam, L., et al. Circ. Res. 107(1):117-125(2010)
Kumar, A., et al. PLoS ONE 5 (10), E13390 (2010) :

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