癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FA96A Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9H5X1 |
| Other Accession | Q9DCL2, Q3T0U7, NP_115607.1 |
| Reactivity | Human, Rat, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 18355 Da |
| Antigen Region | 109-138 aa |
| Gene ID | 84191 |
|---|---|
| Other Names | MIP18 family protein FAM96A, FAM96A |
| Target/Specificity | This FA96A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the C-terminal region of human FA96A. |
| Dilution | WB~~1:2000 IHC-P~~N/A IF~~1:50~200 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.05% (V/V) Proclin 300. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FA96A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CIAO2A (HGNC:26235) |
|---|---|
| Function | Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Substantially enriched in macrophages. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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¥ 1,250.00
Cat# AP11250b
