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>   首页   >   产品   >   一抗   >   心血管   >   HBQ1 Antibody (N-term)   

HBQ1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - HBQ1 Antibody (N-term) AP12996a
    HBQ1 Antibody (N-term) (Cat. #AP12996a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HBQ1 antibody detected the HBQ1 protein (arrow).
  • 14 - HBQ1 Antibody (N-term) AP12996a
    HBQ1 Antibody (N-term) (Cat. #AP12996a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HBQ1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P09105
Other Accession NP_005322.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 15508 Da
Antigen Region 1-28 aa
Additional Information
Gene ID 3049
Other Names Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin, HBQ1
Target/Specificity This HBQ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human HBQ1.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHBQ1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HBQ1
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.

REFERENCES

De Gobbi, M., et al. Science 312(5777):1215-1217(2006)
Patrinos, G.P., et al. Hum. Mutat. 26(5):399-412(2005)
Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
Giardina, B., et al. Crit. Rev. Biochem. Mol. Biol. 30(3):165-196(1995)
Kim, J.H., et al. Nucleic Acids Res. 17(14):5687-5700(1989)

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