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ASAM Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ASAM Antibody (Center) AP13037c
    ASAM Antibody (Center) (Cat. #AP13037c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ASAM antibody detected the ASAM protein (arrow).
  • 14 - ASAM Antibody (Center) AP13037c
    ASAM Antibody (Center) (Cat. #AP13037c)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ASAM Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-P-Leica, E
Primary Accession Q9H6B4
Other Accession Q8K1G0, Q8R373, NP_079045.1
Reactivity Human, Mouse, Rat
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41281 Da
Antigen Region 81-110 aa
Additional Information
Gene ID 79827
Other Names CXADR-like membrane protein, Adipocyte adhesion molecule, Coxsackie- and adenovirus receptor-like membrane protein, CAR-like membrane protein, CLMP, ACAM, ASAM
Target/Specificity This ASAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human ASAM.
Dilution WB~~1:1000
IHC-P~~1:100~500
IHC-P-Leica~~N/A
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsASAM Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLMP
Synonyms ACAM, ASAM
Function May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.
Cellular Location Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue. Expressed at high levels in small intestine and placenta, at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney and lung and at low levels in the liver and peripheral blood leukocytes. Highly abundant in the intestine during embryo and fetal development (at protein level)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The CTX (see VSIG2, MIM 606011) family of proteins, including ASAM, are type I transmembrane proteins within the Ig superfamily that localize to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion (Raschperger et al., 2004 [PubMed 14573622]).[supplied by OMIM].

REFERENCES

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kawabata, K., et al. Gene Ther. 14(16):1199-1207(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Eguchi, J., et al. Biochem. J. 387 (PT 2), 343-353 (2005) :
Raschperger, E., et al. J. Biol. Chem. 279(1):796-804(2004)

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