DTX3 Antibody (N-term )
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
---|---|
Primary Accession | Q8N9I9 |
Other Accession | Q80V91, NP_848597.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 37988 Da |
Antigen Region | 20-48 aa |
Gene ID | 196403 |
---|---|
Other Names | Probable E3 ubiquitin-protein ligase DTX3, 632-, Protein deltex-3, Deltex3, RING finger protein 154, DTX3, RNF154 |
Target/Specificity | This DTX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of human DTX3. |
Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DTX3 Antibody (N-term ) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DTX3 |
---|---|
Synonyms | RNF154 |
Function | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
Cellular Location | Cytoplasm. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).
REFERENCES
Chastagner, P., et al. EMBO Rep. 7(11):1147-1153(2006)
Takeyama, K., et al. J. Biol. Chem. 278(24):21930-21937(2003)
Kishi, N., et al. Int. J. Dev. Neurosci. 19(1):21-35(2001)
Matsuno, K., et al. Development 121(8):2633-2644(1995)

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.
Discontinued
Cat# AP13476a
Size:
50 µl
100 µl
200 µl
400 µl
Price:
¥ 1,250.00
¥ 2,050.00
¥ 2,960.00
¥ 4,550.00
替代产品: