Anti-Wnt3a Antibody
Mouse Anti Human Monoclonal Antibody
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Application ![]()
| WB |
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Primary Accession | P56704 |
Other Accession | NM_033131 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Immunogen | Purified recombinant Wnt3a protein fragments expressed in E.coli. |
Purification | Affinity purified |
Calculated MW | 39365 Da |
Gene ID | 89780 |
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Other Names | MGC119418 ;MGC119419 ;MGC119420 ;Protein Wnt 3a Precursor ;Protein Wnt-3a ;Wingless type MMTV integration site family member 3A ;Wnt 3a ;wnt3a ;WNT3A protein ;WNT3A_HUMAN. |
Dilution | WB~~1:1000 |
Format | PBS(pH 7.4) containing with 0.09% (W/V) sodium azide and 50% glycerol. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | WNT3A |
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Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20093360, PubMed:21244856, PubMed:24841207, PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720). |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P27467}. Secreted |
Tissue Location | Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.

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Discontinued
Cat# AP53397