YWHAZ Antibody
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB |
---|---|
Primary Accession | P63104 |
Other Accession | P63102, P63101, P63103 |
Reactivity | Human, Mouse, Rat |
Predicted | Bovine |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 27745 Da |
Isotype | IgG2b,κ |
Antigen Source | HUMAN |
Gene ID | 7534 |
---|---|
Antigen Region | 1-261 aa |
Other Names | 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ |
Dilution | WB~~1:1000 |
Target/Specificity | This YWHAZ antibody is generated from a mouse immunized with a recombinant protein from human YWHAZ. |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | YWHAZ Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | YWHAZ |
---|---|
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:14578935, PubMed:15071501, PubMed:15644438, PubMed:16376338, PubMed:16959763, PubMed:31024343, PubMed:9360956). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:35662396). Binding generally results in the modulation of the activity of the binding partner (PubMed:35662396). Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB (PubMed:35662396). Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity). |
Cellular Location | Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
REFERENCES
Zupan L.A.,et al.J. Biol. Chem. 267:8707-8710(1992).
Seluja G.A.,et al.Biochim. Biophys. Acta 1395:281-287(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.