Interactive Apoptosis Pathway

Apoptosis (programmed cell death) is characterized by cell shrinkage, membrane blebbing, phagocytic engulfment of the fragmented cell, DNA fragmentation and mitochondrial release of cytochrome C. Tightly regulated termination is essential to cull unneeded, aging, mutated, or infected cells. Dysregulation of death/survival signals in the apoptotic pathway is implicated in a broad range of human diseases. Controlling fidelity of the apoptotic pathways may lead to new methods to treat challenging diseases.
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