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>   首页   >   产品   >   一抗   >   心血管   >   Anti-TNFRSF1B / TNFR2 Antibody   

Anti-TNFRSF1B / TNFR2 Antibody

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E, Neut
Primary Accession P20333
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 48291 Da
Additional Information
Gene ID 7133
Alias Symbol TNFRSF1B
Other Names TNFRSF1B, CD120b antigen, CD120b, Etanercept, p75 TNF receptor, Soluble TNFR1B variant 1, TNFBR, Tumor necrosis factor receptor, TNF-R-II, TNF-R75, TNFR2, p75TNFR, p80 TNF-alpha receptor, TBPII, TNF-R2, TNFR80, TNF-RII, TNFR-II, TNFR1B
Target/Specificity Human sTNF Receptor-II
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-TNFRSF1B / TNFR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF1B
Synonyms TNFBR, TNFR2
Function Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Cellular Location [Isoform 1]: Cell membrane; Single-pass type I membrane protein [Tumor necrosis factor-binding protein 2]: Secreted
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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