癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SOD2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 2
- 实验流程
- 背景知识
Application 
| WB, FC, E |
|---|---|
| Primary Accession | P04179 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24750 Da |
| Gene ID | 6648 |
|---|---|
| Other Names | Superoxide dismutase [Mn], mitochondrial, SOD2 |
| Target/Specificity | This SOD2 antibody is generated from rabbits immunized with human recombinant SD protein. |
| Dilution | WB~~1:1000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SOD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOD2 |
|---|---|
| Function | Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. |
| Cellular Location | Mitochondrion matrix. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.
REFERENCES
Fabre,E.E., Am. J. Clin. Nutr. 87 (5), 1504-1512 (2008) Kaewpila,S., Cancer Res. 68 (8), 2781-2788 (2008) Flekac,M., (er) BMC Med. Genet. 9, 30 (2008)
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