PUMA Antibody [2A9G5]
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
---|---|
Primary Accession | Q9BXH1 |
Other Accession | Q9BXH1, 56748610 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 2A9G5 |
Calculated MW | 20532 Da |
Concentration (mg/ml) | 1 mg/mL |
Conjugate | Unconjugated |
Application Notes | PUMA antibody can be used for detection of PUMA by Western blot at 2.5 to 5 µg/mL. |
Gene ID | 27113 |
---|---|
Other Names | Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3, PUMA |
Target/Specificity | BBC3; |
Reconstitution & Storage | PUMA monoclonal antibody can be stored at -20℃, stable for one year. |
Precautions | PUMA Antibody [2A9G5] is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BBC3 |
---|---|
Synonyms | PUMA |
Function | Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis (PubMed:11463391, PubMed:23340338). Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis (PubMed:23340338). Regulates ER stress-induced neuronal apoptosis (By similarity). |
Cellular Location | Mitochondrion Note=Localized to the mitochondria in order to induce cytochrome c release |
Tissue Location | Ubiquitously expressed. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.

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Discontinued
Cat# ASC11980
Size:
0.1 mg
Price:
¥ 5,587.00
替代产品: