孕激素受体抗体试剂(免疫组织化学)
Rabbit Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
Application ![]()
| IHC |
---|---|
Primary Accession | P06401 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 278G8D6 |
Calculated MW | 98981 Da |
Gene ID | 5241 |
---|---|
Gene Name | PGR |
Other Names | Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3 |
Dilution | IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C. |
Precautions | PR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PGR |
---|---|
Synonyms | NR3C3 |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor. |
Cellular Location | Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases [Isoform 4]: Mitochondrion outer membrane |
Tissue Location | In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region-specific responses to hormonal stimuli |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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