RANBP3L Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

RANBP3L Antibody (Center) (Cat. #AP13762c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RANBP3L antibody detected the RANBP3L protein (arrow).
RANBP3L Antibody (Center) (Cat. #AP13762c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RANBP3L Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, E
Primary Accession	Q86VV4
Other Accession	NP_659437.3, NP_001154901.1
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Calculated MW	52211 Da
Antigen Region	137-165 aa

Additional Information
Gene ID	202151
Other Names	Ran-binding protein 3-like, RANBP3L
Target/Specificity	This RANBP3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the Central region of human RANBP3L.
Dilution	WB~~1:1000 IHC-P~~1:100~500 E~~Use at an assay dependent concentration.
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions	RANBP3L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	RANBP3L
Function	Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.
Cellular Location	Nucleus. Cytoplasm

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

Application Protocols

Provided below are standard protocols that you may find useful for product applications.