癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MX2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB |
|---|---|
| Primary Accession | P20592 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Calculated MW | 82 KDa |
| Gene ID | 4600 |
|---|---|
| Other Names | Interferon-induced GTP-binding protein Mx2, Interferon-regulated resistance GTP-binding protein MxB, Myxovirus resistance protein 2, p78-related protein, MX2 |
| Dilution | WB~~1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | MX2 |
|---|---|
| Function | Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. |
| Cellular Location | Cytoplasm. Nucleus. Nucleus, nuclear pore complex. Note=Localization to nuclear pores requires GTP-binding |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
REFERENCES
Aebi M.,et al.Mol. Cell. Biol. 9:5062-5072(1989).
Hattori M.,et al.Nature 405:311-319(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Horisberger M.A.,et al.J. Virol. 64:1171-1181(1990).
King M.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:8957-8962(2004).
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