癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NFIC Antibody
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, ICC |
|---|---|
| Primary Accession | P08651 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Calculated MW | 55675 Da |
| Gene ID | 4782 |
|---|---|
| Other Names | 1110019L22Rik;1500041O16Rik;AA589446;AI746521;CAAT box transcription factor;CCAAT binding transcription factor;CCAAT box binding transcription factor;CCAAT-box-binding transcription factor;CNFI C;CTF;CTF5;MGC137374;MGC20153;NF I;NF I/C;NF-I/C;NF1 C;NF1-C; NF1C;NFI;NFI-C;NFI/C;NFIC;NFIC_HUMAN;Nuclear factor 1;Nuclear factor 1 C type;Nuclear factor 1 C-type;Nuclear factor 1/C;Nuclear factor I/C;TGGCA binding protein;TGGCA-binding protein;Transcription factor NFIC. |
| Dilution | WB~~1:200 ICC~~1:200 |
| Format | ascites |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NFIC |
|---|---|
| Synonyms | NFI |
| Function | Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. |
| Cellular Location | Nucleus. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
REFERENCES
Santoro C.,et al.Nature 334:218-224(1988).
Wenzelides S.,et al.Nucleic Acids Res. 24:2416-2421(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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