癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NFIC Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant NFIC.
- 产品详情
- 实验流程
Application 
| WB, IHC, IF |
|---|---|
| Primary Accession | P08651 |
| Other Accession | BC012120 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1C12-2A2 |
| Calculated MW | 55675 Da |
| Gene ID | 4782 |
|---|---|
| Other Names | Nuclear factor 1 C-type, NF1-C, Nuclear factor 1/C, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/C, NF-I/C, NFI-C, TGGCA-binding protein, NFIC, NFI |
| Target/Specificity | NFIC (AAH12120, 1 a.a. ~ 428 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NFIC Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells. Udelhoven M, et al. J Mol Endocrinol, 2010 Feb. PMID 19755487.Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression. Plasari G, et al. Mol Cell Biol, 2009 Nov. PMID 19752192.Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family. Riffel AK, et al. Mol Pharmacol, 2009 Nov. PMID 19706729.Nuclear factor I transcription factors regulate IGF binding protein 5 gene transcription in human osteoblasts. P?rez-Casellas LA, et al. Biochim Biophys Acta, 2009 Feb. PMID 18809517.
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