癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CHD4 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IP |
|---|---|
| Primary Accession | Q14839 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Calculated MW | 260 KDa |
| Gene ID | 1108 |
|---|---|
| Other Names | ATP dependent helicase CHD4;ATP-dependent helicase CHD4;CHD 4;CHD-4;CHD4;CHD4_HUMAN; Chromodomain helicase DNA binding protein 4;Chromodomain-helicase-DNA-binding protein 4;DKFZp686E06161;Mi 2 autoantigen 218 kDa protein;Mi 2b;Mi-2 autoantigen 218 kDa protein;Mi2 beta;Mi2-beta. |
| Dilution | WB~~1:1000 IP~~1:500 |
| Format | Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CHD4 |
|---|---|
| Function | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. |
| Cellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Associates with centrosomes in interphase {ECO:0000250|UniProtKB:Q6PDQ2} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
REFERENCES
Seelig H.P.,et al.Arthritis Rheum. 38:1389-1399(1995).
Scherer S.E.,et al.Nature 440:346-351(2006).
Tong J.K.,et al.Nature 395:917-921(1998).
Schmidt D.R.,et al.Biochemistry 38:14711-14717(1999).
Kim J.,et al.Immunity 10:345-355(1999).
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