癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-AFP Antibody
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Application 
| IHC-P |
|---|---|
| Primary Accession | P02773 |
| Host | Mouse |
| Isotype | Mouse IgG2a |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Lyophilized |
| Description | Mouse IgG monoclonal antibody for AFP, alpha-fetoprotein (AFP) detection. Tested with IHC-P in Human. No cross reactivity with other proteins. |
| Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Other Names | Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, Afp |
|---|---|
| Calculated MW | 68386 Da |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 2-4 µg/ml, Human, By Heat |
| Subcellular Localization | Isoform 1: Secreted. |
| Tissue Specificity | Plasma. . |
| Source | Eukaryota |
| Protein Name | Alpha-fetoprotein |
| Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Clone Names | C3 |
| Immunogen | Human alpha-fetoprotein. |
| Purification | Ascites |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the ALB/AFP/VDB family. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Afp |
|---|---|
| Function | Binds estrogens, fatty acids and metals. |
| Cellular Location | [Isoform 1]: Secreted. |
| Tissue Location | Plasma.. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Alpha-fetoprotein(AFP) is a major plasma protein in the fetus, where it is produced by the yolk sac and liver. Direct confirmation of the assignment of the AFP gene to chromosome 4 by in situ hybridization was provided by Harper and Dugaiczyk(1983), who placed the gene in the q11-q22 region, the same region as the albumin gene. Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.As the major fetal serum protein, Alpha-fetoprotein is not essential for embryonic development but is required for female fertility.
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