Anti-MAP2 Antibody (Monoclonal, HM-2)
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Application
| WB, IHC-P |
|---|---|
| Primary Accession | P15146 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal |
| Format | Lyophilized |
| Description | Mouse IgG monoclonal antibody for MAP2, microtubule-associated protein 2 (MAP2) detection. Tested with WB, IHC-P in Human;mouse;rat. No cross reactivity with other proteins. |
| Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Gene ID | 25595 |
|---|---|
| Other Names | Microtubule-associated protein 2, MAP-2, Map2, Mtap2 |
| Calculated MW | 202411 Da |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 1-2 µg/ml, Human, mouse, rat, By Heat Western blot, 0.5-2 µg/ml, Human, mouse, rat |
| Subcellular Localization | Cytoplasm, cytoskeleton . |
| Source | Eukaryota |
| Protein Name | Microtubule-associated protein 2 |
| Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Clone Names | HM-2 |
| Immunogen | Rat brain microtubule-associated proteins(MAPs). |
| Purification | Ascites |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Contains 3 Tau/MAP repeats. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Map2 |
|---|---|
| Synonyms | Mtap2 |
| Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, dendrite {ECO:0000250|UniProtKB:P20357} |
| Tissue Location | [Isoform 2]: Expressed in the liver. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2(MAP2)is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.
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