Anti-SFTPA1 Antibody
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Application
| WB |
|---|---|
| Primary Accession | Q8IWL2 |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Clonality | Polyclonal |
| Format | Liquid |
| Description | Rabbit IgG polyclonal antibody for Pulmonary surfactant-associated protein A1(SFTPA1) detection. Tested with WB in Human;Rat. |
| Gene ID | 653509 |
|---|---|
| Other Names | Pulmonary surfactant-associated protein A1, PSP-A, PSPA, SP-A, SP-A1, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4, SFTPA1, COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B |
| Calculated MW | 26242 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Rat |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
| Source | Eukaryota |
| Protein Name | Pulmonary surfactant-associated protein A1(PSP-A/PSPA/SP-A/SP-A1) |
| Contents | Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free" or "No BSA" in your order note. " |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1(221-236aa KEQCVEMYTDGQWNDR), different from the rat sequence by two amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the SFTPA family. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SFTPA1 |
|---|---|
| Synonyms | COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B |
| Function | In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity). |
| Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.
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