癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-CD90/Thy1 Antibody
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Application 
| WB |
|---|---|
| Primary Accession | P04216 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Thy-1 membrane glycoprotein(THY1) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 7070 |
|---|---|
| Other Names | Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, CD90, THY1 |
| Calculated MW | 17935 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Rat, Human, Mouse |
| Subcellular Localization | Cell membrane ; Lipid-anchor, GPI-anchor . |
| Source | Eukaryota |
| Protein Name | Thy-1 membrane glycoprotein |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CD90(20-39aa QKVTSLTACLVDQSLRLDCR), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | THY1 |
|---|---|
| Function | May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI- anchor |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CD90(Cluster of Differentiation 90) or Thy-1 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol(GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. The CD90 gene is mapped to 11q23.3. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor.
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