癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Cortisol Binding Globulin Antibody
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Application 
| WB, IHC-P, ICC |
|---|---|
| Primary Accession | P08185 |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Corticosteroid-binding globulin(SERPINA6) detection. Tested with WB, IHC-P, ICC in Human. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 866 |
|---|---|
| Other Names | Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG |
| Calculated MW | 45141 Da |
| Application Details | Immunocytochemistry , 0.5-1 µg/ml, Human, - Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, By Heat Western blot, 0.1-0.5 µg/ml, Human |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Source | Eukaryota |
| Protein Name | Corticosteroid-binding globulin |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Cortisol Binding Globulin(102-120aa ETEIHQGFQHLHQLFAKSD). |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the serpin family. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SERPINA6 |
|---|---|
| Synonyms | CBG |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Corticosteroid-binding globulin(CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
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