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Anti-EPB41L1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q9H4G0 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Band 4.1-like protein 1(EPB41L1) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 2036 |
|---|---|
| Other Names | Band 4.1-like protein 1, Neuronal protein 4.1, 4.1N, EPB41L1, KIAA0338 |
| Calculated MW | 98503 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Mouse, Rat, Human |
| Subcellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Specificity | Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle. |
| Source | Eukaryota |
| Protein Name | Band 4.1-like protein 1 |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human EPB41L1(585-604aa QDQERDTVFLKDNHLAIERK), different from the related mouse and rat sequences by one amino acid. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Contains 1 FERM domain. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | EPB41L1 (HGNC:3378) |
|---|---|
| Function | May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | Highest expression in brain, lower in heart, kidney, pancreas, placenta, lung and skeletal muscle |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. EPB41L1 has been shown to interact with ITPR1, Dopamine receptor D2, Dopamine receptor D3, CENTG1 and Nuclear mitotic apparatus protein 1.
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