癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Rab3C Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q96E17 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Ras-related protein Rab-3C(RAB3C) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 115827 |
|---|---|
| Other Names | Ras-related protein Rab-3C, RAB3C |
| Calculated MW | 25952 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse |
| Subcellular Localization | Cell membrane ; Lipid-anchor ; Cytoplasmic side . |
| Tissue Specificity | Expressed in brain, placenta and lung. . |
| Source | Eukaryota |
| Protein Name | Ras-related protein Rab-3C |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3C(204-217aa AITAAKQNTRLKET), different from the related mouse and rat sequences by one amino acid. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | RAB3C (HGNC:30269) |
|---|---|
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Tissue Location | Expressed in brain, placenta and lung. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene. It is mapped to 5q11.2. RAB3C is found in brain, adrenal gland and pituitary. This gene is one of the small GTPases implicated in the regulation of vesicular trafficking between membrane compartments. RAB3C gene contains 6 exons and spans more than 310 kb. The function of this gene is transporting protein, and probably involved in vesicular traffic. RAB3C can interact with RIMS2, RPH3A and RPH3AL.
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