癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Fetuin A Picoband Antibody
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Application 
| WB |
|---|---|
| Primary Accession | P29699 |
| Host | Rabbit |
| Reactivity | Mouse |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Alpha-2-HS-glycoprotein(AHSG) detection. Tested with WB in Mouse. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 11625 |
|---|---|
| Other Names | Alpha-2-HS-glycoprotein, Countertrypin, Fetuin-A, Ahsg, Fetua |
| Calculated MW | 37326 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Mouse |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Liver is the major site of synthesis, but fetuin is also expressed in limb buds and other extrahepatic tissues during development. |
| Source | Eukaryota |
| Protein Name | Alpha-2-HS-glycoprotein |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Immunogen | E.coli-derived mouse Fetuin A recombinant protein (Position: A19-I345). Mouse Fetuin A shares 57% and 85% amino acid (aa) sequence identity with human and rat Fetuin A, respectively. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the fetuin family. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Ahsg |
|---|---|
| Synonyms | Fetua |
| Function | Probably involved in differentiation. |
| Cellular Location | Secreted. |
| Tissue Location | Liver is the major site of synthesis, but fetuin is also expressed in limb buds and other extrahepatic tissues during development |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Alpha-2-HS-glycoprotein (AHSG) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. Fetuin-A belongs to the fetuin class of plasma binding proteins and is more abundant in fetal than adult blood. This gene is mapped to 3q27. Fetuin-A is a secreted partially phosphorylated glycoprotein with complex proeolytic processing that circulates in blood and extracellular fluids. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuin-A is also a potent inhibitor of pathological calcification.
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