癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-OMG Picoband Antibody
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- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P23515 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Oligodendrocyte-myelin glycoprotein(OMG) detection. Tested with WB in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 4974 |
|---|---|
| Other Names | Oligodendrocyte-myelin glycoprotein, OMG, OMGP |
| Calculated MW | 49608 Da |
| Application Details | Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Specificity | Oligodendrocytes and myelin of the central nervous system. |
| Source | Eukaryota |
| Protein Name | Oligodendrocyte-myelin glycoprotein |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human OMG (64-99aa YNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR), different from the related mouse sequence by two amino acids. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins. |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | OMG |
|---|---|
| Synonyms | OMGP |
| Function | Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Location | Oligodendrocytes and myelin of the central nervous system |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.
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