Anti-OPRD1/Delta Opioid Receptor Rabbit Monoclonal Antibody
- 产品详情
- 实验流程
Application
| WB, FC |
|---|---|
| Primary Accession | P41143 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-OPRD1/Delta Opioid Receptor Rabbit Monoclonal Antibody . Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 4985 |
|---|---|
| Other Names | Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1, OPRD |
| Calculated MW | 40369 Da |
| Application Details | WB 1:1000-1:2000 FC 1:50 |
| Subcellular Localization | Cell membrane ; Multi- pass membrane protein. |
| Tissue Specificity | Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.. |
| Source | Eukaryota |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: GFC-15 |
| Immunogen | A synthesized peptide derived from human OPRD1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | OPRD1 |
|---|---|
| Synonyms | OPRD |
| Function | G protein-coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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