癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Human Cytochrome C DyLight® 488 conjugated CYCS Antibody(monoclonal, 15F10)
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- 实验流程
- 背景知识
Application 
| FC |
|---|---|
| Primary Accession | P99999 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Human Cytochrome C DyLight® 488 conjugated CYCS Antibody (monoclonal, 15F10) . Tested in Flow Cytometry applications. This antibody reacts with Human. |
| Gene ID | 54205 |
|---|---|
| Other Names | Cytochrome c, CYCS, CYC |
| Calculated MW | 11749 Da |
| Application Details | Flow Cytometry, 1-3 µg/1x10^6 cells |
| Subcellular Localization | Mitochondrion intermembrane space. Loosely associated with the inner membrane. |
| Source | Eukaryota |
| Contents | Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3. |
| Clone Names | Clone: 15F10 |
| Immunogen | E.coli-derived human Cytochrome C recombinant protein (Position: G2-E105). Human Cytochrome C shares 91% amino acid (aa) sequence identity with both mouse and rat Cytochrome C. |
| Cross Reactivity | No cross-reactivity with other proteins. |
| Storage | At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CYCS |
|---|---|
| Synonyms | CYC |
| Function | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. |
| Cellular Location | Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
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